Boxer Floyd Mayweather and rapper 50 Cent, aka Curtis James Jackson III, reignited their longtime social media spats this weekend, with the two trading barbs about herpes, domestic violence and illiteracy.

Both Mayweather, 41, and 50 Cent, 43, continued feuding on Instagram Saturday, with the former The Money Team friends laying into each other’s private lives. In a lengthy Instagram post, Mayweather went after “Curtis ‘Confidential Informant’ Jackson” and his relationship with he and Shaniqua Tompkins’ son, Marquise. In response, the Get Rich or Die Tryin’ rapper went after Mayweather’s alleged inability to read or write.